<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10028" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2015-05-29</depositionDate>
            <releaseDate>2015-06-17</releaseDate>
            <updateDate>2023-03-28</updateDate>
        </keyDates>
        <title>Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine</title>
        <correspondingAuthor>
            <authorORCID>0000-0002-0462-6540</authorORCID>
            <firstName>Sjors</firstName>
            <middleName>SHW</middleName>
            <lastName>Scheres</lastName>
            <organization type="academic">Structural Studies, Medical Research Council Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 OQH</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0002-0462-6540</authorORCID>
            <firstName>Sjors</firstName>
            <middleName>SHW</middleName>
            <lastName>Scheres</lastName>
            <organization type="academic">Structural Studies, Medical Research Council Laboratory of Molecular Biology</organization>
            <street>Francis Crick Avenue</street>
            <townOrCity>Cambridge</townOrCity>
            <stateOrProvince>Cambridgeshire</stateOrProvince>
            <country>United Kingdom</country>
            <postOrZipCode>CB2 OQH</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author>Wong W</author>
            <author>Bai XC</author>
            <author>Brown A</author>
            <author>Fernandez IS</author>
            <author>Hanssen E</author>
            <author>Condron M</author>
            <author>Tan YH</author>
            <author>Baum J</author>
            <author authorORCID="0000-0002-0462-6540">Scheres SHW</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
        </grantSupport>
        <datasetSize units="TB">1.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-10028</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-2660</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Wong W</author>
                    <author authorORCID="0000-0002-4234-5686" order="2">Bai XC</author>
                    <author authorORCID="0000-0002-0021-0476" order="3">Brown A</author>
                    <author order="4">Fernandez IS</author>
                    <author authorORCID="0000-0002-4064-1844" order="5">Hanssen E</author>
                    <author order="6">Condron M</author>
                    <author order="7">Tan YH</author>
                    <author authorORCID="0000-0002-0275-352X" order="8">Baum J</author>
                    <author authorORCID="0000-0002-0462-6540" order="9">Scheres SH</author>
                    <title>Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine</title>
                    <journal>eLife</journal>
                    <journalAbbreviation>Elife</journalAbbreviation>
                    <country></country>
                    <volume>3</volume>
                    <year>2014</year>
                    <language>English</language>
                    <externalReferences type="doi">10.7554/elife.03080</externalReferences>
                    <externalReferences type="pubmed">24913268</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned multi-frame micrographs</name>
        <directory>/data/Micrographs</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>1081</numImagesOrTiltSeries>
        <framesPerImage>16</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.34</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.34</pixelHeight>
        </dimensions>
        <details>Micrographs are split into two sub-directories: Micrographs_part1 and Micrographs_part2. Each of these directories contains BOTH the unaligned frames (xxx_movie.mrcs) and the frame-averaged micrographs (600.mrc). These directories also contain the ctffind3 log files and the autopick star files.</details>
        <segmentationList/>
    </imageSet>
    <imageSet>
        <name>Frame averaged micrographs</name>
        <directory>/data/Micrographs</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>1081</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4096</imageWidth>
            <pixelWidth>1.34</pixelWidth>
            <imageHeight>4096</imageHeight>
            <pixelHeight>1.34</pixelHeight>
        </dimensions>
        <details>Micrographs are split into two sub-directories: Micrographs_part1 and Micrographs_part2. Each of these directories contains BOTH the unaligned frames (xxx_movie.mrcs) and the frame-averaged micrographs (600.mrc). These directories also contain the ctffind3 log files and the autopick star files.</details>
        <segmentationList/>
    </imageSet>
    <imageSet>
        <name>Processed shiny particles</name>
        <directory>/data/Particles</directory>
        <category>picked particles - multiframe - processed</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>105247</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>360</imageWidth>
            <pixelWidth>1.34</pixelWidth>
            <imageHeight>360</imageHeight>
            <pixelHeight>1.34</pixelHeight>
        </dimensions>
        <details>Particle images are organized in two sub-directories - MRC_0601 and MRC_1901. Particle images are in MRCS image stacks - one each corresponding to the micrograph from which they were picked. The text file shiny_2sets.star describes the picking of the particles from the micrographs.</details>
        <segmentationList/>
    </imageSet>
</entry>
