Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core

REL 2015-10-12 2015-10-13 2015-10-13 Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core Paula da Fonseca MRC Laboratory of Molecular Biology Cambridge Biomedical Campus; Francis Crick Avenue Cambridge CB2 0QH United Kingdom CB2 0QH Paula da Fonseca MRC Laboratory of Molecular Biology Cambridge Biomedical Campus; Francis Crick Avenue Cambridge CB2 0QH United Kingdom CB2 0QH da Fonseca PCA Morris EP 579.1 10.6019/EMPIAR-10038 EMDB EMD-2981 raw micrographs of the human 20S proteasome core complex bound to the ligand AdaAhx3L3VS /data/micrographs micrographs - multiframe MRC MRC 545 17 1 17 32 BIT FLOAT 4096 1.04 4096 1.04

raw micrographs recorded as 17 movie frames in a 1s exposure, with each frame corresponding to an electron dose of 2.8 electrons per squared Angstrom