human 26S proteasome bound to the chemotherapeutic Oprozomib

REL 2018-03-21 2018-03-21 2018-03-21 human 26S proteasome bound to the chemotherapeutic Oprozomib 0000-0002-5276-5633 David Haselbach Institute of Molecular Pathology Vienna Biocenter 1 Vienna Vienna Austria 1030 Holger Stark Max-Planck-Institute for biophysical Chemistry Am Faßberg 11 Göttingen Niedersachsen Germany 37077 Haselbach D Schrader J Lambrecht F Henneberg F Chari A Stark H 100.5 10.6019/EMPIAR-10166 EMDB EMD-4146 Haselbach D Schrader J Lambrecht F Henneberg F Chari A Stark H Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs Nature communications Nat Commun 8 15578 15586 2017 English 10.1038/ncomms15578 28541292 Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib. /data picked particles - single frame - processed MRCS MRCS 238631 40 0 40 32 BIT FLOAT 336 1.27 336 1.27

Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib. Total dose 40 electrons per Angstroem squared. Images are already inverted and normalized.