<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10219" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2018-10-08</depositionDate>
            <releaseDate>2018-10-23</releaseDate>
            <updateDate>2019-09-25</updateDate>
        </keyDates>
        <title>Cryo-electron microscopy data of thermostabilized avian CFTR</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0003-1822-2384</authorORCID>
            <firstName>Jonathan</firstName>
            <middleName>Firoze</middleName>
            <lastName>fay</lastName>
            <organization type="academic">University of North Carolina Chapel Hill</organization>
            <street>98 Manning Drive</street>
            <townOrCity>Chapel Hill</townOrCity>
            <stateOrProvince>NC</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>27599</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0003-1822-2384</authorORCID>
            <firstName>Jonathan</firstName>
            <middleName>Firoze</middleName>
            <lastName>fay</lastName>
            <organization type="academic">University of North Carolina Chapel Hill</organization>
            <street>98 Manning Drive</street>
            <townOrCity>Chapel Hill</townOrCity>
            <stateOrProvince>NC</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>27599</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0003-1822-2384">Fay JF</author>
        </authorsList>
        <datasetSize units="GB">19.3</datasetSize>
        <entryDOI>10.6019/EMPIAR-10219</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-7793</emdbEntry>
            <emdbEntry>EMD-7794</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-1822-2384" order="1">Fay JF</author>
                    <author order="2">Aleksandrov LA</author>
                    <author order="3">Jensen T</author>
                    <author order="4">Cui L</author>
                    <author order="5">Kousouros JN</author>
                    <author order="6">He L</author>
                    <author order="7">Aleksandrov AA</author>
                    <author order="8">Gingerich D</author>
                    <author order="9">Riordan JR</author>
                    <author order="10">Chen J</author>
                    <title>Cryo-EM visualization of an active high open probability CFTR anion channel</title>
                    <journal>Biochemistry</journal>
                    <journalAbbreviation>Biochemistry</journalAbbreviation>
                    <country>United States</country>
                    <year>2018</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1021/acs.biochem.8b00763</externalReferences>
                    <externalReferences type="pubmed">30281975</externalReferences>
                    <details>Two particle stacks and meta-data associated with entries EMD-7793 &amp; EMD-7794.</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Binned Particle stacks and meta data for cryo-EM structures of phosphorylated and dephosphorylated avian CFTR</name>
        <directory>/data</directory>
        <category>picked particles - multiframe - processed</category>
        <headerFormat>MRCS</headerFormat>
        <dataFormat>MRCS</dataFormat>
        <numImagesOrTiltSeries>2</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>variable</imageWidth>
            <pixelWidth>variable</pixelWidth>
            <imageHeight>variable</imageHeight>
            <pixelHeight>variable</pixelHeight>
        </dimensions>
        <details>Binned Particle stacks and meta data for cryo-EM structures of phosphorylated and dephosphorylated avian CFTR
7793: PPase-treated CFTR : 200x200, 30,219 images @ 1.37 A/pix 
7794: PKA-treated CFTR : 160x160, 57,826 images @ 1.71 A/pix</details>
        <segmentationList/>
        <micrographsFilePattern>data/7793.mrcs</micrographsFilePattern>
        <pickedParticlesFilePattern>data/7793.star</pickedParticlesFilePattern>
        <pickedParticlesDirectory>data</pickedParticlesDirectory>
    </imageSet>
</entry>
