<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-10752" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2021-07-04</depositionDate>
            <releaseDate>2021-10-01</releaseDate>
            <updateDate>2022-02-25</updateDate>
        </keyDates>
        <title>Single particle cryo EM Data of a human Akirin2 proteasome complex</title>
        <correspondingAuthor>
            <authorORCID>0000-0002-5276-5633</authorORCID>
            <firstName>David</firstName>
            <lastName>Haselbach</lastName>
            <organization type="academic">IMP - Research Institute of Molecular Pathology</organization>
            <street>Campus Vienna Biocenter 1</street>
            <townOrCity>Vienna</townOrCity>
            <stateOrProvince>Vienna</stateOrProvince>
            <country>Austria</country>
            <postOrZipCode>1110</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator>
            <authorORCID>0000-0002-5276-5633</authorORCID>
            <firstName>David</firstName>
            <lastName>Haselbach</lastName>
            <organization type="academic">IMP - Research Institute of Molecular Pathology</organization>
            <street>Campus Vienna Biocenter 1</street>
            <townOrCity>Vienna</townOrCity>
            <stateOrProvince>Vienna</stateOrProvince>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </principalInvestigator>
        <principalInvestigator>
            <authorORCID>0000-0001-8810-6835</authorORCID>
            <firstName>Johannes</firstName>
            <lastName>Zuber</lastName>
            <organization type="academic">IMP - Research Institute of Molecular Pathology</organization>
            <street>Campus Vienna Biocenter 1</street>
            <townOrCity>Vienna</townOrCity>
            <stateOrProvince>Vienna</stateOrProvince>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0003-4871-2069">de Almeida M</author>
            <author authorORCID="0000-0003-2435-4690">Hinterndorfer M</author>
            <author authorORCID="0000-0002-3446-3738">Brunner H</author>
            <author authorORCID="0000-0003-0164-9373">Grishkovskaya I</author>
            <author authorORCID="0000-0002-9891-8148">Singh K</author>
            <author authorORCID="0000-0001-6251-2747">Schleiffer A</author>
            <author>Jude J</author>
            <author>Deswal S</author>
            <author authorORCID="0000-0001-7553-4806">Kalis R</author>
            <author authorORCID="0000-0001-6330-363X">Vunjak M</author>
            <author authorORCID="0000-0003-4596-9512">Lendl T</author>
            <author>Imre R</author>
            <author authorORCID="0000-0002-3405-7801">Roitinger E</author>
            <author authorORCID="0000-0003-3908-4224">Neumann T</author>
            <author authorORCID="0000-0002-4007-6283">Kandolf S</author>
            <author>Schutzbier M</author>
            <author authorORCID="0000-0002-3392-9946">Mechtler K</author>
            <author authorORCID="0000-0002-6150-2165">Versteeg GA</author>
            <author authorORCID="0000-0002-5276-5633">Haselbach D</author>
            <author authorORCID="0000-0001-8810-6835">Zuber J</author>
        </authorsList>
        <datasetSize units="TB">2.0</datasetSize>
        <entryDOI>10.6019/EMPIAR-10752</entryDOI>
        <experimentType>EMDB</experimentType>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-12341</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0003-4871-2069" order="1">de Almeida M</author>
                    <author authorORCID="0000-0003-2435-4690" order="2">Hinterndorfer M</author>
                    <author authorORCID="0000-0002-3446-3738" order="3">Brunner H</author>
                    <author authorORCID="0000-0003-0164-9373" order="4">Grishkovskaya I</author>
                    <author authorORCID="0000-0002-9891-8148" order="5">Singh K</author>
                    <author authorORCID="0000-0001-6251-2747" order="6">Schleiffer A</author>
                    <author order="7">Jude J</author>
                    <author order="8">Deswal S</author>
                    <author authorORCID="0000-0001-7553-4806" order="9">Kalis R</author>
                    <author authorORCID="0000-0001-6330-363X" order="10">Vunjak M</author>
                    <author authorORCID="0000-0003-4596-9512" order="11">Lendl T</author>
                    <author order="12">Imre R</author>
                    <author authorORCID="0000-0002-3405-7801" order="13">Roitinger E</author>
                    <author authorORCID="0000-0003-3908-4224" order="14">Neumann T</author>
                    <author authorORCID="0000-0002-4007-6283" order="15">Kandolf S</author>
                    <author order="16">Schutzbier M</author>
                    <author authorORCID="0000-0002-3392-9946" order="17">Mechtler K</author>
                    <author authorORCID="0000-0002-6150-2165" order="18">Versteeg GA</author>
                    <author authorORCID="0000-0002-5276-5633" order="19">Haselbach D</author>
                    <author authorORCID="0000-0001-8810-6835" order="20">Zuber J</author>
                    <title>AKIRIN2 controls the nuclear import of proteasomes in vertebrates</title>
                    <journal>Nature</journal>
                    <journalAbbreviation>Nature</journalAbbreviation>
                    <country></country>
                    <issue>7885</issue>
                    <volume>599</volume>
                    <firstPage>491</firstPage>
                    <lastPage>496</lastPage>
                    <year>2021</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41586-021-04035-8</externalReferences>
                    <externalReferences type="pubmed">34711951</externalReferences>
                    <details>Raw micrographs of Akirin2 bound to the proteasome</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Unaligned Multiframe micrographs of Akirin2 bound to the human proteasome</name>
        <directory>/data/rawmics</directory>
        <category>micrographs - multiframe</category>
        <headerFormat>TIFF</headerFormat>
        <dataFormat>TIFF</dataFormat>
        <numImagesOrTiltSeries>4595</numImagesOrTiltSeries>
        <framesPerImage>50</framesPerImage>
        <voxelType>UNSIGNED BYTE</voxelType>
        <dimensions>
            <imageWidth>4092</imageWidth>
            <pixelWidth>1.06</pixelWidth>
            <imageHeight>5760</imageHeight>
            <pixelHeight>1.06</pixelHeight>
        </dimensions>
        <details>movie files of Akirin2 recorded witha dose of 50 e-/s ona. K3 camera</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Motion corrected files dose weighted and summed as well as without dose weigthening</name>
        <directory>/data/motioncorrected</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>9190</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>4092</imageWidth>
            <pixelWidth>1.06</pixelWidth>
            <imageHeight>5760</imageHeight>
            <pixelHeight>1.06</pixelHeight>
        </dimensions>
        <details>Patch motion corrected files from cryosparc</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
    <imageSet>
        <name>Extracted particles of an Akirin2 bound proteasome</name>
        <directory>/data/extracted_particles</directory>
        <category>picked particles - single frame - processed</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>165181</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>560</imageWidth>
            <pixelWidth>1.06</pixelWidth>
            <imageHeight>560</imageHeight>
            <pixelHeight>1.06</pixelHeight>
        </dimensions>
        <details>relion extracted particle stack.</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
