REL
2021-07-27
2022-07-26
2022-07-26
Cryo electron microscopy final particle stacks of Substance P-Neurokinin Receptor G protein complexes
0000-0002-7173-3741
Aashish
Manglik
Department of Pharmaceutical Chemistry, University of California, San Francisco
600 16th Street
San Francisco
California
United States
94158
0000-0002-7173-3741
Aashish
Manglik
Department of Pharmaceutical Chemistry, University of California, San Francisco
600 16th Street
San Francisco
California
United States
94158
0000-0001-9535-0369
Yifan
Cheng
Department of Biochemistry & Biophysics, University of California, San Francisco
600 16th Street
San Francisco
California
United States
94158
0000-0002-0325-2524
David
M
Thal
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University
Wellington Rd
Melbourne
Victoria
Australia
3800
Harris JA
Faust B
170.8
10.6019/EMPIAR-10786
EMDB
molecule
EMD-24569
EMD-24570
EMD-24572
Harris JA
Faust B
Gondin AB
Dämgen MA
Suomivuori CM
Veldhuis NA
Cheng Y
Dror RO
Thal DM
Manglik A
Selective G protein signaling driven by substance P-neurokinin receptor dynamics
Nature chemical biology
Nat Chem Biol
1
18
109
115
2021
English
10.1038/s41589-021-00890-8
34711980
This deposition contains the final particle stacks and .star files used to reconstruct the Substance P-bound NK1R-miniGs/q70-Nb35, Substance P-bound NK1R-miniGs399-Nb35 and Substance P(6-11)-bound NK1R-miniGs/q70-Nb35 complexes.
Harris JA
Faust B
Gondin AB
Dämgen MA
Suomivuori C
Veldhuis NA
Cheng Y
Dror RO
Thal DM
Manglik A
Selective G protein signaling driven by Substance P-Neurokinin Receptor structural dynamics
bioRxiv
2021
10.1101/2021.05.16.444192
This deposition contains the final particle stacks and .star files used to reconstruct the Substance P-bound NK1R-miniGs/q70-Nb35, Substance P-bound NK1R-miniGs399-Nb35 and Substance P(6-11)-bound NK1R-miniGs/q70-Nb35 complexes.
Particle stack and final .star file for SP-NK1R-miniGs399 reconstruction
/data/SP-NK1R-miniGs399 final particle stack and .star file
picked particles - single frame - processed
MRCS
MRCS
288659
60
32 BIT FLOAT
variable
0.86
variable
0.86
This directory contains the final particle stack and .star file containing shifts/poses for the published SP-NK1R-miniGs399 reconstruction.
Particle stack and final .star file for SP6-11-NK1R-miniGsq70 reconstruction
/data/SP6-11-NK1R-miniGsq70 final particle stack and .star file
picked particles - single frame - processed
MRCS
MRCS
59926
120
32 BIT FLOAT
variable
0.835
variable
0.835
This directory contains the final particle stack and .star file containing shifts/poses for the published SP6-11-NK1R-miniGsq70 reconstruction.
Particle stack and final .star file for SP-NK1R-miniGsq70 reconstruction
/data/SP-NK1R-miniGsq70 final particle stack and .star file
picked particles - single frame - processed
MRCS
MRCS
122220
120
32 BIT FLOAT
variable
0.835
variable
0.835
This directory contains the final particle stack and .star file containing shifts/poses for the published SP-NK1R-miniGsq70 reconstruction.