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        <keyDates>
            <depositionDate>2022-04-28</depositionDate>
            <releaseDate>2024-11-21</releaseDate>
            <updateDate>2024-11-21</updateDate>
        </keyDates>
        <title>Human platelets in presence of SARS-CoV-2 spike protein</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0001-9304-8027</authorORCID>
            <firstName>Christopher</firstName>
            <middleName>Cyrus</middleName>
            <lastName>Kuhn</lastName>
            <organization type="academic">Laboratory of Structural Cell Biology, NHLBI/NIH</organization>
            <street>50 South Drive</street>
            <townOrCity>Bethesda</townOrCity>
            <stateOrProvince>MD</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>20892</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-1594-2821</authorORCID>
            <firstName>Naoko</firstName>
            <lastName>Mizuno</lastName>
            <organization type="academic">Laboratory of Structural Cell Biology, NHLBI/NIH</organization>
            <street>50 South Drive</street>
            <townOrCity>Bethesda</townOrCity>
            <stateOrProvince>MD</stateOrProvince>
            <country>United States</country>
            <postOrZipCode>20892</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author>Basnet N</author>
            <author authorORCID="0000-0002-0448-7683">Bodakuntla S</author>
            <author>Nichols S</author>
            <author authorORCID="0000-0002-5865-2138">Martinez-Sanchez A</author>
            <author>Agostini L</author>
            <author authorORCID="0000-0002-3804-7168">Soh YM</author>
            <author authorORCID="0000-0002-1219-475X">Takagi J</author>
            <author authorORCID="0000-0002-7528-6547">Biertumpfel C</author>
            <author authorORCID="0000-0002-1594-2821">Mizuno N</author>
        </authorsList>
        <grantSupport>
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                <fundingBody></fundingBody>
                <code></code>
                <country></country>
            </grantReference>
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        <datasetSize units="GB">15.3</datasetSize>
        <entryDOI>10.6019/EMPIAR-11038</entryDOI>
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        <scale>cell</scale>
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    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-26794</emdbEntry>
            <emdbEntry>EMD-26796</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author order="1">Kuhn CC</author>
                    <author order="2">Basnet N</author>
                    <author order="3">Bodakuntla S</author>
                    <author order="4">Alvarez-Brecht P</author>
                    <author order="5">Nichols S</author>
                    <author authorORCID="0000-0002-5865-2138" order="6">Martinez-Sanchez A</author>
                    <author authorORCID="0000-0001-6742-4519" order="7">Agostini L</author>
                    <author authorORCID="0000-0002-3804-7168" order="8">Soh YM</author>
                    <author authorORCID="0000-0002-1219-475X" order="9">Takagi J</author>
                    <author order="10">Biertümpfel C</author>
                    <author authorORCID="0000-0002-1594-2821" order="11">Mizuno N</author>
                    <title>Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 spike protein</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country></country>
                    <issue>1</issue>
                    <volume>14</volume>
                    <year>2023</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-023-36279-5</externalReferences>
                    <externalReferences type="pubmed">36739444</externalReferences>
                    <details>Reconstructed volumes</details>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Reconstructed 4x binned tomograms from human platelets in presence of SARS-CoV-2 spike protein</name>
        <directory>/data</directory>
        <category>reconstructed volumes</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>6</numImagesOrTiltSeries>
        <framesPerImage>6</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>1023</imageWidth>
            <pixelWidth>11.04</pixelWidth>
            <imageHeight>1440</imageHeight>
            <pixelHeight>11.04</pixelHeight>
        </dimensions>
        <details>The reconstructed volumes were obtained from 61 tilts</details>
        <segmentationList/>
        <micrographsFilePattern></micrographsFilePattern>
        <pickedParticlesFilePattern></pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
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