REL 2023-03-22 2023-04-13 2023-04-13 Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2 0000-0001-5121-2036 Axel T Brunger Department of Molecular and Cellular Physiology 318 Campus Drive, Room E300 Stanford California United States 94305 0000-0002-8234-1997 Kailu Yang Howard Hughes Medical Institute; Stanford University 318 Campus Drive, Room E300 Stanford California United States 94305 Yang K Brunger AT 4.6 10.6019/EMPIAR-11475 EMDB molecule EMD-27098 Yang K Wang C Kreutzberger AJB Ojha R Kuivanen S Couoh-Cardel S Muratcioglu S Eisen TJ White KI Held RG Subramanian S Marcus K Pfuetzner RA Esquivies L Doyle CA Kuriyan J Vapalahti O Balistreri G Kirchhausen T Brunger AT Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A 40 119 2022 English 10.1073/pnas.2210990119 36122200 Unaligned multi-frame micrographs of the scaffolded HR1HR2 complex with extended HR2 /data/20210416_COVID258_TEM1_130K/Movies micrographs - multiframe TIFF TIFF 18846 40 UNSIGNED BYTE 11520 0.3265 8184 0.3265
Please refer to the published paper for details.