REL
2023-09-18
2024-08-29
2024-08-29
Cryo-EM micrographs of human DNA polymerase θ helicase domain bound to inhibitor AB25583
0000-0002-2274-118X
Fumiaki
Ito
University of Southern California
1050 Childs Way RRI 103
Los Angeles
CA
United States
90089
0000-0002-2274-118X
Fumiaki
Ito
University of Southern California
1050 Childs Way RRI 103
Los Angeles
CA
United States
90089
Ito F
Li Z
Minakhin L
Chandramouly G
Tyagi M
Betsch R
Krais JJ
Tiberi B
Johnson N
Chen XS
Pomerantz RT
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R01GM130889
United States
4.9
10.6019/EMPIAR-11711
EMDB
molecule
EMD-44765
EMD-44766
Ito F
Li Z
Minakhin L
Chandramouly G
Tyagi M
Betsch R
Krais JJ
Taberi B
Vekariya U
Calbert M
Skorski T
Johnson N
Chen XS
Pomerantz RT
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM
Nature communications
Nat Commun
1
15
2024
English
10.1038/s41467-024-51351-4
39143110
Unaligned multi-frame micrographs of human DNA polymerase θ helicase domain bound to inhibitor AB25583
/data/20230223_USC_fumiakii_f4_polQ-H_grid4
micrographs - multiframe
EER
EER
4500
2051
BIT
4096
0.92
4096
0.92
We recommend dividing the total frames into 40 frame movies for motion correction. The gain reference image is in the root folder, it does not need to be flipped or rotated.
data/20230223_USC_fumiakii_f4_polQ-H_grid4/Images-Disc1/*/*/*.eer