REL
2023-11-27
2025-02-21
2025-02-21
AL amyloid fibril from the FOR010 light chain
0000-0002-9442-460X
Matthias
Schmidt
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
0000-0003-2123-6816
Marcus
Fändrich
Institut für Proteinbiochemie, Universität Ulm
8/1 Helmholtzstrasse
Ulm
Baden Württemberg
Germany
89081
Pfeiffer PB
Banerjee S
Schmidt M
Fändrich M
German Research Foundation (DFG)
FA 456/23
Germany
1.8
10.6019/EMPIAR-11802
EMDB
molecule
EMD-18881
Karimi-Farsijani S
Pfeiffer PB
Banerjee S
Baur J
Kuhn L
Kupfer N
Hegenbart U
Schönland SO
Wiese S
Haupt C
Schmidt M
Fändrich M
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
Unaligned multi-frame micrographs of FOR010 amyloid fibrils
/data/eer
micrographs - multiframe
EER
EER
4008
963
BIT
4096
0.934
4096
0.934
IC-Krios1 G4 300kV C-FEG
SelectrisX 10eV slit width, Falcon4i
Cs=2.7mm, C2aperture=50um, ObjAperture=100um
EFTEM 130kx, nanoprobe spot 5, beam=630nm
Counting mode, 1pix=0.934 A
~3 s exposure, EER files save (963 fractions, not gain corrected)
~40 e/A^2 total dose
The gain reference (/data/micrographs/20220808_133943_EER_GainReference.gain) is not applied to the micrographs. The NOTES.txt file contains EM information. Thumbnails and power spectra (data/thumbnails) as well as coordinates (/data/Manual_Pick) are provided.
data/eer/*.eer
data/Manual_Pick/*.star
data/Manual_Pick