<entry xmlns="http://pdbe.org/empiar" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="https://ftp.ebi.ac.uk/pub/databases/emtest/empiar/schema/empiar.xsd" accessionCode="EMPIAR-12237" schemaVersion="0.65" public="true">
    <admin>
        <currentStatus>REL</currentStatus>
        <keyDates>
            <depositionDate>2024-07-26</depositionDate>
            <releaseDate>2025-04-07</releaseDate>
            <updateDate>2025-04-07</updateDate>
        </keyDates>
        <title>Micrographs of S.cerevisiae pre-60S particles (Nsa1-Tap) of usnic acid treated and untreated cells.</title>
        <correspondingAuthor private="true">
            <authorORCID>0000-0002-0365-5913</authorORCID>
            <firstName>Lorenz</firstName>
            <lastName>Grundmann</lastName>
            <organization type="academic">Institute of molecular pathology (Haselbach Lab)</organization>
            <street>Campus-Vienna-Biocenter 1</street>
            <townOrCity>Wien, 03. Bezirk</townOrCity>
            <stateOrProvince>Vienna</stateOrProvince>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </correspondingAuthor>
        <principalInvestigator private="true">
            <authorORCID>0000-0002-5276-5633</authorORCID>
            <firstName>David</firstName>
            <lastName>Haselbach</lastName>
            <organization type="academic">Institute of molecular pathology (Haselbach Lab)</organization>
            <street>Campus-Vienna-Biocenter 1</street>
            <townOrCity>Wien, 03. Bezirk</townOrCity>
            <stateOrProvince>Vienna</stateOrProvince>
            <country>Austria</country>
            <postOrZipCode>1030</postOrZipCode>
        </principalInvestigator>
        <authorsList>
            <author authorORCID="0000-0002-7724-309X">Bergler H</author>
        </authorsList>
        <grantSupport>
            <grantReference>
                <fundingBody>Austrian Science Fund</fundingBody>
                <code>DOI:10.55776/P32977</code>
                <country>Austria</country>
            </grantReference>
        </grantSupport>
        <datasetSize units="GB">667.2</datasetSize>
        <entryDOI>10.6019/EMPIAR-12237</entryDOI>
        <experimentType>EMDB</experimentType>
        <scale>molecule</scale>
    </admin>
    <crossReferences>
        <relatedEMDBEntries>
            <emdbEntry>EMD-51122</emdbEntry>
            <emdbEntry>EMD-51126</emdbEntry>
            <emdbEntry>EMD-51128</emdbEntry>
            <emdbEntry>EMD-51129</emdbEntry>
            <emdbEntry>EMD-51164</emdbEntry>
            <emdbEntry>EMD-51165</emdbEntry>
            <emdbEntry>EMD-51166</emdbEntry>
            <emdbEntry>EMD-51167</emdbEntry>
        </relatedEMDBEntries>
        <citationList>
            <universalCitation>
                <journalCitation published="true" preprint="false">
                    <author authorORCID="0000-0002-0365-5913" order="1">Grundmann L</author>
                    <author order="2">Kofler L</author>
                    <author order="3">Gerhalter M</author>
                    <author authorORCID="0000-0002-2526-9896" order="4">Prattes M</author>
                    <author authorORCID="0000-0002-3422-4083" order="5">Merl-Pham J</author>
                    <author order="6">Zisser G</author>
                    <author authorORCID="0000-0003-0164-9373" order="7">Grishkovskaya I</author>
                    <author authorORCID="0000-0003-3904-947X" order="8">Hodirnau VV</author>
                    <author order="9">Vareka M</author>
                    <author authorORCID="0000-0001-6009-7359" order="10">Breinbauer R</author>
                    <author authorORCID="0000-0002-1630-6827" order="11">Hauck SM</author>
                    <author authorORCID="0000-0002-5276-5633" order="12">Haselbach D</author>
                    <author authorORCID="0000-0002-7724-309X" order="13">Bergler H</author>
                    <editor authorORCID="0000-0002-5276-5633" order="1">Haselbach D</editor>
                    <title>The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation</title>
                    <journal>Nature communications</journal>
                    <journalAbbreviation>Nat Commun</journalAbbreviation>
                    <country>Austria</country>
                    <issue>1</issue>
                    <volume>15</volume>
                    <year>2024</year>
                    <language>English</language>
                    <externalReferences type="doi">10.1038/s41467-024-51754-3</externalReferences>
                    <externalReferences type="pubmed">39209816</externalReferences>
                </journalCitation>
            </universalCitation>
        </citationList>
    </crossReferences>
    <imageSet>
        <name>Patch motion corrected</name>
        <directory>/data</directory>
        <category>micrographs - single frame</category>
        <headerFormat>MRC</headerFormat>
        <dataFormat>MRC</dataFormat>
        <numImagesOrTiltSeries>7595</numImagesOrTiltSeries>
        <framesPerImage>1</framesPerImage>
        <voxelType>32 BIT FLOAT</voxelType>
        <dimensions>
            <imageWidth>5760</imageWidth>
            <pixelWidth>1.07</pixelWidth>
            <imageHeight>4092</imageHeight>
            <pixelHeight>1.07</pixelHeight>
        </dimensions>
        <details>Particle coordinates are provided both as star (*.star) and cs (*.cs) file. Each cluster has its own coordinate file. Information on how to seperate particles from the usnic acid treated or untreated dataset can be found in the particles/README.txt file</details>
        <segmentationList/>
        <micrographsFilePattern>data/motioncorrected/*.mrc</micrographsFilePattern>
        <pickedParticlesFilePattern>data/particles/*.star</pickedParticlesFilePattern>
        <pickedParticlesDirectory></pickedParticlesDirectory>
    </imageSet>
</entry>
