Cryo electron micrographs of AP-3 core bound to Arf1 and LAMPI on a lipid nanodisc

REL 2024-09-27 2024-12-21 2024-12-21 Cryo electron micrographs of AP-3 core bound to Arf1 and LAMPI on a lipid nanodisc 0000-0003-1136-6000 Richard Baker Department of Biochemistry and Biophysics, UNC Chapel Hill School of Medicine Chapel Hill North Carolina United States 27519 0000-0003-1136-6000 Richard Baker Department of Biochemistry and Biophysics, UNC Chapel Hill School of Medicine Chapel Hill North Carolina United States 27519 Baker RW Begley M National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) R35GM150960 United States 1018.6 10.6019/EMPIAR-12311 EMDB molecule EMD-45207 EMD-45210 EMD-45211 EMD-45212 EMD-45213 EMD-45208 EMD-45209 Begley M Aragon M Baker RW A structure-based mechanism for initiation of AP-3 coated vesicle formation bioRxiv 2024 10.1101/2024.06.05.597630 38895279

The micrographs are motion-corrected with dose weighting in cryoSPARCv4.4.1. There are four separate datasets, each collected at a unique tilt angle.

aligned, dose-weighted micrographs of AP-3 core and Arf1 Q71L bound to a nanodisc containing LAMP1 cargo peptide /data/nanodisc_AP-3 micrographs - single frame MRC MRC 11601 1 32 BIT FLOAT 5760 1.058 4092 1.058