REL
2024-08-20
2025-04-07
2025-04-07
Cryo-EM Structures of human LINE-1 ORF2p target-primed reverse transcription complex
0000-0002-2180-3430
Thi Hoang Duong
Nguyen
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
Cambridgeshire
United Kingdom
CB2 0QH
0000-0002-2180-3430
Thi Hoang Duong
Nguyen
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge
Cambridgeshire
United Kingdom
CB2 0QH
0000-0002-3341-3122
George
E
Ghanim
Princeton University
N/A
Princeton
New Jersey
United States
08544
Ghanim GEG
UK Research and Innovation (UKRI)
MC_UP_1201/19
United Kingdom
Jane Coffin Childs (JCC) Fund
na
United States
5.1
10.6019/EMPIAR-12450
EMDB
molecule
EMD-52070
EMD-52071
EMD-52072
EMD-52073
Ghanim GE
Hu H
Boulanger J
Nguyen THD
Structural mechanism of LINE-1 target-primed reverse transcription
Science (New York, N.Y.)
Science
2025
English
10.1126/science.ads8412
40048554
Unaligned multi-frame micrographs of the human LINE-1 ORF2p TPRT complex
/data/Micrographs
micrographs - multiframe
TIFF
TIFF
25374
50
UNSIGNED BYTE
4096
0.955
4096
0.955
These are movie files in TIFF format. Associated gain reference for the dataset is also included in TIFF format.
Polished particle stack of the ORF2p TPRT complex consensus reconstruction (EMD-52070)
/data/ParticleStacks/EMD-52070
picked particles - single frame - processed
MRCS
MRCS
680273
1
UNSIGNED BYTE
4096
0.955
4096
0.955