REL
2026-01-19
2026-01-29
2026-01-29
Cryo electron microscopy of modified human GABA(A) receptors reconstituted in lipid nanodiscs with the ligand GABOB
0000-0003-2049-3378
Rebecca
J
Howard
Stockholm University
SciLifeLab, Box 1031
Solna
Sweden
17121
0000-0002-2734-2794
Erik
Lindahl
Stockholm University
Box 1031
Solna
Sweden
17121
Fan C
Cowgill J
Howard RJ
Lindahl E
Swedish Research Council
2019-02433, 2021-05806
Sweden
Knut and Alice Wallenberg Foundation
2023.0254
Sweden
168.5
10.6019/EMPIAR-13222
EMDB
molecule
EMD-50713
EMD-50714
Fan C
Cowgill J
Howard RJ
Lindahl E
Cryo-EM structures of ρ1 GABA(A) receptors with antagonist and agonist drugs
Nature Communications
Nat Commun
1
16
2025
English
10.1038/s41467-025-61932-6
40750757
Polished particles from two refined densities from a single cryo-EM dataset
Images containing particles associated with the desensitized state
/data/Polish/Desen/k3_frames_b/Images-Disc1
picked particles - multiframe - processed
MRCS
MRCS
18711
4
32 BIT FLOAT
420
0.67
420
1.0
Particle positions in corresponding cs files
data/Polish/Desen/k3_frames_b/Images-Disc1/GridSquare_1893****/Data/FoilHole_********_Data_********_0_202403**_******_fractions_shiny.mrcs
data/Polish/Desen/shiny_desensitized.star
data/J655_desen
Images containing particles associated with the partially locked state
/data/Polish/Primed/k3_frames_b/Images-Disc1
picked particles - multiframe - processed
MRCS
MRCS
21062
4
1
4
32 BIT FLOAT
420
0.67
420
1.0
Particle positions in corresponding cs files
data/Polish/Primed/k3_frames_b/Images-Disc1/GridSquare_1893****/Data/FoilHole_********_Data_********_0_202403**_******_fractions_shiny.mrcs
data/Polish/Primed/shiny_primed.star
data/J661_primed