Ribosomal RNA modifications around the peptidyl transfer center stimulate catalytic activity and prevent the formation of alternative structures

REL 2026-01-23 2026-03-23 2026-03-23 Ribosomal RNA modifications around the peptidyl transfer center stimulate catalytic activity and prevent the formation of alternative structures 0000-0001-7683-6419 Daniel S.D. Larsson Department of Cell and Molecular Biology, Uppsala University Husargatan 3 Uppsala Sweden 75237 0000-0001-9079-2774 Maria Selmer Department of Cell and Molecular Biology, Uppsala University Husargatan 3 Uppsala Sweden 75237 Larsson DSD Selmer M Swedish Research Council 2016-06264 Sweden Swedish Research Council 2017-03827 Sweden Swedish Research Council 2022-04511 Sweden Estonian Research Council PUT PRG1179 Estonia 7.7 10.6019/EMPIAR-13296 EMDB molecule EMD-55349 EMD-55427 EMD-55428 EMD-55429 EMD-55430 EMD-55432 EMD-55433 EMD-55434 EMD-55435 EMD-55436 EMD-55437 EMD-55415 EMD-55467 EMD-55468 EMD-55469 EMD-55470 EMD-55471 EMD-55472 EMD-55473 EMD-55474 EMD-55475 EMD-55476 EMD-55618 EMD-55702 EMD-55703 EMD-55704 EMD-55705 EMD-55706 EMD-55707 EMD-55708 EMD-55709 EMD-55710 EMD-55711 Larsson DSD Liiv A Ero R Remme J Selmer M Ribosomal RNA modifications around the peptidyl transfer center stimulate catalytic activity and prevent the formation of alternative structures Unaligned multi-frame micrographs of 70S ribosomes from delta-9 strain /data/delta9 micrographs - multiframe MRC MRC 9602 20 1 20 UNSIGNED BYTE 3838 0.8215 3710 0.8215

Detector Gatan K2, total exposure dose 30.0 e/Å2, gain corrected

data/delta9/raw_data/GridSquare_*/Data/FoilHole_*.mrc Unaligned multi-frame micrographs of 70S ribosomes from delta-10 strain /data/delta10 micrographs - multiframe TIFF TIFF 8488 20 1 20 UNSIGNED BYTE 3838 0.8215 3710 0.8215

Detector Gatan K2, total exposure dose 30.0 e/Å2, non-gain corrected, LZW compressed

data/delta10/raw_data/FoilHole_*.tif Unaligned multi-frame micrographs of 70S ribosomes from delta-RlmE strain /data/deltaRlmE micrographs - multiframe TIFF TIFF 10436 39 1 39 UNSIGNED BYTE 5760 0.8228 4092 0.8228

Detector Gatan K3, total exposure dose 40.6 e/Å2, gain corrected, LZW compressed

data/deltaRlmE/raw_data/GridSquare_*/Data/FoilHole_*_fractions.tiff