REL
2025-02-17
2026-04-09
2026-04-09
Nanodisc-embedded human TF/FVIIa/XK1
0000-0002-1553-4772
Amanda
Photenhauer
Life Sciences Institute, University of Michigan Ann Arbor
210 Washtenaw Ave
Ann Arbor
Michigan
United States
48109
0000-0003-1750-4793
Melanie
D
Ohi
Life Sciences Institute, University of Michigan
210 Washtenaw Ave
Ann Arbor
Michigan
United States
48109
0000-0002-1570-1569
James
H
Morrissey
Department of Biological Chemistry, University of Michigan Medical School
4301B MSRB III, 1150 West Medical Center Drive
Ann Arbor
MI
United States
48109
Sedzro JC
Photenhauer AL
Ohi MD
Morrissey JH
National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)
R35 HL135823
United States
National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)
R35 HL171334
United States
National Institutes of Health/Office of the Director
S10OD030275
United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
R24 GM145965
United States
American Heart Association
N028347
United States
4.8
10.6019/EMPIAR-13365
EMDB
molecule
EMD-71094
Sedzro JC
Photenhauer AL
Birkle F
Meze K
Mortenson A
Duckworth C
Wen P
Kearns S
Cianfrocco MA
Tajkhorshid E
Ohi MD
Morrissey JH
Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism
Blood
English
10.1182/blood.2025029430
40811856
Nanodisc-embedded human TF/FVIIa/XK1
Unaligned image stacks of nanodisc-embedded human tissue factor in complex with factor VIIa and XK1, a factor X mimetic
/data/tifs
micrographs - multiframe
TIFF
TIFF
20088
50
0
49
UNSIGNED BYTE
5760
0.834
4092
0.834
Particle positions contained in .star file. Unaligned micrographs in TIF format. Total accumulated dose of 49.7 electrons per square angstrom. Nominal magnification of 105,000kx corresponds to pixel spacing of 0.834 Angstrom per pixel (differs from mdoc file/header).
data/tifs/2023-07-31_14.11.22_0000_X-1Y-1-1.tif
data/particles/J3276_particles_exported.star
data/particles
Gain reference for unaligned image stacks of nanodisc-embedded human tissue factor in complex with factor VIIa and XK1, a factor X mimetic
/data
micrographs - single frame
MRC
MRC
1
1
UNSIGNED BYTE
5760
0.834
4092
0.834
Gain reference in .mrc format
data/CountRef_2023-07-31_14.11.22_0000_X-1Y-1-1.mrc